商品介绍
- Specification
- Product Description:
- Anti-TARDBP is intended for the semi-quantitative detection of TAR DNA Binding Protein (TARDBP ) in paraffin sections.
- Immunogen:
- TARDBP (NP_031401.1, 1 a.a. ~ 260 a.a) recombinant protein with GST tag.
- Host:
- Mouse
- Specificity:
- Human TAR DNA binding protein
- Isotype:
- IgG1, kappa
- Storage Buffer:
- In 1x PBS, pH 7.2
- Storage Instruction:
- Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
- Note:
- Product image
- Protocol:
Protocol Download
- Regulation Status:
- USA:IVD Class 1(FDA Registered Establishment Number: 3007539499)Taiwan:產品名稱: 亞諾法免疫組織化學染色單株抗體 (未滅菌) (TAR去氧核糖核酸結合酶-43單株抗體)許可證字號: 衛署醫器製壹字第004544號 (醫療器材管理辦法「免疫組織化學試劑與套組(B.1860)」第一等級鑒別範圍)
- Datasheet:
- Download
- Clone Name:
- Monoclonal antibody (S1)
- Applications
- Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
enlarge this image- Immunoperoxidase of monoclonal antibody to TARDBP on formalin-fixed paraffin-embedded human lung. [antibody concentration 0.75 ug/ml]
- Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
enlarge this image- Immunoperoxidase of monoclonal antibody to TARDBP on formalin-fixed paraffin-embedded human pancreas. [antibody concentration 0.75 ug/ml]
- Application Image
- Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
- enlarge
- Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
- enlarge
- Gene Information
- Entrez GeneID:
- 23435
- Gene Name:
- TARDBP
- Gene Alias:
- ALS10,TDP-43
- Gene Description:
- TAR DNA binding protein
- Omim ID:
- 605078
- Gene Ontology:
- Hyperlink
- Gene Summary:
- HIV-1, the causative agent of acquired immunodeficiency syndrome (AIDS), contains an RNA genome that produces a chromosomally integrated DNA during the replicative cycle. Activation of HIV-1 gene expression by the transactivator Tat is dependent on an RNA regulatory element (TAR) located downstream of the transcription initiation site. The protein encoded by this gene is a transcriptional repressor that binds to chromosomally integrated TAR DNA and represses HIV-1 transcription. In addition, this protein regulates alternate splicing of the CFTR gene. A similar pseudogene is present on chromosome 20. [provided by RefSeq
- Other Designations:
- OTTHUMP00000002171,TAR DNA-binding protein-43
- Related Disease
- Alzheimer Disease
- Amyotrophic Lateral Sclerosis
- Amyotrophic lateral sclerosis
- Chromosome Disorders
- Dementia
- Genetic Predisposition to Disease
- Neurodegenerative Diseases
- Parkinson Disease
- Parkinson disease
品牌介绍
Abnova公司是专注于高通量蛋白表达和抗体制作，并将世界级的生物技术与台湾IT工业管理经验独特融于一体的全球性生物公司。Abnova通过基因组 学手段生产出的几万种重组蛋白和抗体，极大的扩展了生物试剂应用的视野和多样性。同时，Abnova还在不断的扩展其在系统应用中的产品线，包括成对抗 体、ELISA试剂盒、原位杂交荧光探针、无表达蛋白定量以及可用于蛋白翻译研究、诊断和制药公司应用的基础型体外诊断设备等。作为Abnova的授权代理商，艾美捷科技有限公司凭借丰富的专业经验，将一如既往的为中国区域客户提供Abnova优质的产品和技术服务。
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