商品介绍
- Specification
- Product Description:
- Anti-STIP1 is intended for the semi-quantitative detection of Stress-induced-phosphoprotein 1 (STIP1) in paraffin sections.
- Immunogen:
- STIP1 (NP_006810.1, 445 a.a. ~ 543 a.a) partial recombinant protein with GST tag.
- Host:
- Mouse
- Specificity:
- Human Stress-induced-phosphoprotein 1
- Isotype:
- IgG2a, kappa
- Storage Buffer:
- In 1x PBS, pH 7.2
- Storage Instruction:
- Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
- Note:
- Product image
- Protocol:
Protocol Download
- Regulation Status:
- USA:IVD Class 1(FDA Registered Establishment Number: 3007539499)Taiwan:產品名稱: 亞諾法免疫組織化學染色單株抗體 (未滅菌) (壓力誘導磷酸化蛋白單株抗體)許可證字號: 衛署醫器製壹字第004544號 (醫療器材管理辦法「免疫組織化學試劑與套組(B.1860)」第一等級鑒別範圍)
- Datasheet:
- Download
- Clone Name:
- Monoclonal antibody (1E3)
- Applications
- Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
enlarge this image- Immunoperoxidase of monoclonal antibody to STIP1 on formalin-fixed paraffin-embedded human ovarian cancer. [antibody concentration 3 ug/ml]
- Application Image
- Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
- enlarge
- Gene Information
- Entrez GeneID:
- 10963
- Gene Name:
- STIP1
- Gene Alias:
- HOP,IEF-SSP-3521,P60,STI1,STI1L
- Gene Description:
- stress-induced-phosphoprotein 1
- Omim ID:
- 605063
- Gene Ontology:
- Hyperlink
- Gene Summary:
- STIP1 is an adaptor protein that coordinates the functions of HSP70 (see HSPA1A; MIM 140550) and HSP90 (see HSP90AA1; MIM 140571) in protein folding. It is thought to assist in the transfer of proteins from HSP70 to HSP90 by binding both HSP90 and substrate-bound HSP70. STIP1 also stimulates the ATPase activity of HSP70 and inhibits the ATPase activity of HSP90, suggesting that it regulates both the conformations and ATPase cycles of these chaperones (Song and Masison, 2005 [PubMed 16100115]).[supplied by OMIM
- Other Designations:
- Hsp70/Hsp90-organizing protein,stress-induced-phosphoprotein 1 (Hsp70/Hsp90-organizing protein)
- Gene Pathway
- Prion diseases
- Related Disease
- Asthma
- Asthma
- Breast cancer
- Breast Neoplasms
- Genetic Predisposition to Disease
- Ovarian cancer
品牌介绍
Abnova公司是专注于高通量蛋白表达和抗体制作，并将世界级的生物技术与台湾IT工业管理经验独特融于一体的全球性生物公司。Abnova通过基因组 学手段生产出的几万种重组蛋白和抗体，极大的扩展了生物试剂应用的视野和多样性。同时，Abnova还在不断的扩展其在系统应用中的产品线，包括成对抗 体、ELISA试剂盒、原位杂交荧光探针、无表达蛋白定量以及可用于蛋白翻译研究、诊断和制药公司应用的基础型体外诊断设备等。作为Abnova的授权代理商，艾美捷科技有限公司凭借丰富的专业经验，将一如既往的为中国区域客户提供Abnova优质的产品和技术服务。
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