商品介绍
- Specification
- Product Description:
- Anti-PGR is intended for the semi-quantitative detection of Progesterone Receptor Type-B (PGR) in paraffin sections.
- Immunogen:
- PGR (NP_000917, 1 a.a. ~ 110 a.a) partial recombinant protein with GST tag.
- Host:
- Mouse
- Specificity:
- Human Progesterone receptor Type-B
- Isotype:
- IgG1, kappa
- Storage Buffer:
- In 1x PBS, pH 7.2
- Storage Instruction:
- Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
- Note:
- Product image
- Protocol:
Protocol Download
- Regulation Status:
- USA:IVD Class 1(FDA Registered Establishment Number: 3007539499)Taiwan:產品名稱: 亞諾法免疫組織化學染色單株抗體 (未滅菌) (黃體激素受體乙型單株抗體)許可證字號: 衛署醫器製壹字第004544號 (醫療器材管理辦法「免疫組織化學試劑與套組(B.1860)」第一等級鑒別範圍)
- Datasheet:
- Download
- Clone Name:
- Monoclonal antibody (2C2)
- Applications
- Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
enlarge this image- Immunoperoxidase of monoclonal antibody to PGR on formalin-fixed paraffin-embedded human breast cancer. [antibody concentration 1.5 ug/ml]
- Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
enlarge this image- Immunoperoxidase of monoclonal antibody to PGR on formalin-fixed paraffin-embedded human ovarian cancer. [antibody concentration 1.5 ug/ml]
- Application Image
- Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
- enlarge
- Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
- enlarge
- Gene Information
- Entrez GeneID:
- 5241
- Gene Name:
- PGR
- Gene Alias:
- NR3C3,PR
- Gene Description:
- progesterone receptor
- Omim ID:
- 607311
- Gene Ontology:
- Hyperlink
- Gene Summary:
- This gene encodes a member of the steroid receptor superfamily. The encoded protein mediates the physiological effects of progesterone, which plays a central role in reproductive events associated with the establishment and maintenance of pregnancy. This gene uses two distinct promotors and translation start sites in the first exon to produce two isoforms, A and B. The two isoforms are identical except for the additional 165 amino acids found in the N-terminus of isoform A only, and mediate their own response genes and physiologic effects with little overlap. The location of transcription initiation for isoform B has not been clearly determined. [provided by RefSeq
- Other Designations:
- -
- Related Disease
- Abortion, Habitual
- Abortion, Spontaneous
- Adenocarcinoma
- Adenocarcinoma, Clear Cell
- Adhesions
- Aortic Aneurysm, Abdominal
- Arthritis, Rheumatoid
- Breast cancer
- Breast Neoplasms
- Carcinoma, Ductal, Breast
- Carcinoma, Endometrioid
- Carcinoma, Lobular
- Cardiovascular Diseases
- Colorectal Neoplasms
- Connective Tissue Diseases
- Diabetes Mellitus, Type 2
- Ductus Arteriosus, Patent
- Edema
- Endometrial Neoplasms
品牌介绍
Abnova公司是专注于高通量蛋白表达和抗体制作，并将世界级的生物技术与台湾IT工业管理经验独特融于一体的全球性生物公司。Abnova通过基因组 学手段生产出的几万种重组蛋白和抗体，极大的扩展了生物试剂应用的视野和多样性。同时，Abnova还在不断的扩展其在系统应用中的产品线，包括成对抗 体、ELISA试剂盒、原位杂交荧光探针、无表达蛋白定量以及可用于蛋白翻译研究、诊断和制药公司应用的基础型体外诊断设备等。作为Abnova的授权代理商，艾美捷科技有限公司凭借丰富的专业经验，将一如既往的为中国区域客户提供Abnova优质的产品和技术服务。
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