商品介绍
- Specification
- Product Description:
- Mouse monoclonal antibody raised against human ANPEP.
- Immunogen:
- KG-1 myeloid cells
- Host:
- Mouse
- Reactivity:
- Human
- Form:
- Liquid
- Purification:
- Protein A/G purification
- Isotype:
- IgG1, kappa
- Recommend Usage:
- Flow Cytometry (0.5-1 ug/106 cells in 0.1 mL)Immunofluorescence (1-2 ug/mL)Immunohistochemistry (Frozen) (0.5-1 ug/mL)The optimal working dilution should be determined by the end user.
- Storage Buffer:
- In 10 mM PBS (0.05% BSA, 0.05% sodium azide)
- Storage Instruction:
- Store at 2 to 8°C.
- Note:
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Datasheet:
Download
- Applications
- Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
- Immunofluorescence
- Flow Cytometry
- Application Image
- Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
- Immunofluorescence
- Flow Cytometry
- Gene Information
- Entrez GeneID:
- 290
- Protein Accession#:
- P15144
- Gene Name:
- ANPEP
- Gene Alias:
- APN,CD13,LAP1,PEPN,gp150,p150
- Gene Description:
- alanyl (membrane) aminopeptidase
- Omim ID:
- 151530
- Gene Ontology:
- Hyperlink
- Gene Summary:
- Aminopeptidase N is located in the small-intestinal and renal microvillar membrane, and also in other plasma membranes. In the small intestine aminopeptidase N plays a role in the final digestion of peptides generated from hydrolysis of proteins by gastric and pancreatic proteases. Its function in proximal tubular epithelial cells and other cell types is less clear. The large extracellular carboxyterminal domain contains a pentapeptide consensus sequence characteristic of members of the zinc-binding metalloproteinase superfamily. Sequence comparisons with known enzymes of this class showed that CD13 and aminopeptidase N are identical. The latter enzyme was thought to be involved in the metabolism of regulatory peptides by diverse cell types, including small intestinal and renal tubular epithelial cells, macrophages, granulocytes, and synaptic membranes from the CNS. Human aminopeptidase N is a receptor for one strain of human coronavirus that is an important cause of upper respiratory tract infections. Defects in this gene appear to be a cause of various types of leukemia or lymphoma. [provided by RefSeq
- Other Designations:
- OTTHUMP00000194690,aminopeptidase M,aminopeptidase N,membrane alanine aminopeptidase,microsomal aminopeptidase
- Gene Pathway
- Glutathione metabolism
- Hematopoietic cell lineage
- Metabolic pathways
- Renin-angiotensin system
- Related Disease
- Genetic Predisposition to Disease
- Hypertension
- Lung Neoplasms
- Tobacco Use Disorder
品牌介绍
Abnova公司是专注于高通量蛋白表达和抗体制作，并将世界级的生物技术与台湾IT工业管理经验独特融于一体的全球性生物公司。Abnova通过基因组 学手段生产出的几万种重组蛋白和抗体，极大的扩展了生物试剂应用的视野和多样性。同时，Abnova还在不断的扩展其在系统应用中的产品线，包括成对抗 体、ELISA试剂盒、原位杂交荧光探针、无表达蛋白定量以及可用于蛋白翻译研究、诊断和制药公司应用的基础型体外诊断设备等。作为Abnova的授权代理商，艾美捷科技有限公司凭借丰富的专业经验，将一如既往的为中国区域客户提供Abnova优质的产品和技术服务。
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总部地址：
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工作时间：周一至周五9:00~18:00
技术支持：
短信：18915418616
服务热线：
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☏ 0512-67156496（苏州）
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