商品介绍
- Specification
- Product Description:
- A2M (Human) ELISA Kit is a competitive enzyme immunoassay for the quantitative measurement of human A2M in plasma and serum.
- Calibration Range:
- 1.25 to 40 ug/mL
- Reactivity:
- Human
- Storage Instruction:
- Store components of the kit at 4°C or -20°C as described in the protocol.
- Protocol:
Protocol Download
- MSDS:
- Download
- Suitable Sample:
- Plasma, Serum
- Sample Volume:
- 25 uL
- Label:
- Peroxidase-conjugated
- Detection Method:
- Colorimetric
- Regulation Status:
- For research use only (RUO)
- Datasheet:
- Download
- Publication Reference
- 1.
- Integrating multiple "omics" analyses identifies serological protein biomarkers for preeclampsia.Liu LY, Yang T, Ji J, Wen Q, Morgan AA, Jin B, Chen G, Lyell DJ, Stevenson DK, Ling XB, Butte AJBMC Med. 2013 Nov 6;11(1):236.
- 2.
- Assessing Candidate Serum Biomarkers for Alzheimer"s Disease: A Longitudinal Study.Zabel M, Schrag M, Mueller C, Zhou W, Crofton A, Petersen F, Dickson A, Kirsch WM.J Alzheimers Dis. 2012 Mar 16. [Epub ahead of print]
- 3.
- Expression of Panza, an alpha2-macroglobulin, in a restricted dorsal domain of the primitive gut in Xenopus laevis.Pineda-Salgado L, Craig EJ, Blank RB, Kessler DS.Gene Expr Patterns. 2005 Dec;6(1):3-10. Epub 2005 Nov 7.
- 4.
- Glomerular deposition of alpha 2-macroglobulin in glomerular diseases.Yang AH, Chen JY.Nephrol Dial Transplant. 1997 Mar;12(3):465-9.
- 5.
- Hepatocyte growth factor and acute phase proteins in patients with chronic liver diseases.Shiota G, Umeki K, Okano J, Kawasaki H.J Med. 1995;26(5-6):295-308.
- Applications
- Quantification
- Application Image
- Quantification
- Gene Information
- Entrez GeneID:
- 2
- Gene Name:
- A2M
- Gene Alias:
- CPAMD5,DKFZp779B086,FWP007,S863-7
- Gene Description:
- alpha-2-macroglobulin
- Omim ID:
- 103950, 104300
- Gene Ontology:
- Hyperlink
- Gene Summary:
- Alpha-2-macroglobulin is a protease inhibitor and cytokine transporter. It inhibits many proteases, including trypsin, thrombin and collagenase. A2M is implicated in Alzheimer disease (AD) due to its ability to mediate the clearance and degradation of A-beta, the major component of beta-amyloid deposits. [provided by RefSeq
- Other Designations:
- -
- Interactome
- Gene Pathway
- Complement and coagulation cascades
- Related Disease
- Alzheimer Disease
- Alzheimer disease
- Amyloidosis
- Arthritis, Rheumatoid
- Cardiovascular Diseases
- Cognition Disorders
- Dementia
- Diabetes Complications
- Diabetes Mellitus, Type 2
- Disease Progression
- Diseases in Twins
- Edema
- Essential Tremor
- Essential tremor
- Genetic Predisposition to Disease
- Hepatitis C, Chronic
- Kidney Failure, Chronic
- Liver Cirrhosis
- Macular Degeneration
品牌介绍
Abnova公司是专注于高通量蛋白表达和抗体制作，并将世界级的生物技术与台湾IT工业管理经验独特融于一体的全球性生物公司。Abnova通过基因组 学手段生产出的几万种重组蛋白和抗体，极大的扩展了生物试剂应用的视野和多样性。同时，Abnova还在不断的扩展其在系统应用中的产品线，包括成对抗 体、ELISA试剂盒、原位杂交荧光探针、无表达蛋白定量以及可用于蛋白翻译研究、诊断和制药公司应用的基础型体外诊断设备等。作为Abnova的授权代理商，艾美捷科技有限公司凭借丰富的专业经验，将一如既往的为中国区域客户提供Abnova优质的产品和技术服务。
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